Frederick Lloyd

  • Previous studies with VEEV and SINV viruses did not provide compelling evidence that these two representative members of the NW and the OW alphaviruses are capable of inducing type I IFN response in cultured cells: SINV usually induced no detectable levels of IFN in commonly used cell lines (Frolova et al., 2002), and VEEV was able to induce only…[Read more]

  • IntroductionMycobacterium bovis is the main causative agent of tuberculosis (TB) in animals. This pathogen has a wide range of hosts (Shrikrishna et al., 2009), including humans, who become infected through ingestion of unpasteurized cow’s milk or milk products, aerosol inhalation, or direct contact with mucous membranes and skin abrasions from i…[Read more]

  • In addition to the sequenced phage genomes, a large number of bacterial genome projects have sequenced many thousands of Enterobacteriaceae genomes. We and others have noted that many prophage sequences are present in these bacterial genome sequences (e.g., Perna et al., 2002; Canchaya et al., 2003; Casjens, 2003). In fact there are many times…[Read more]

  • A potential link, even if still unproven, could be provided by a fourth animal population: the Peccary (Family Tayassuidae). In particular the collared peccary (Pecari tajacu) and white-lipped peccary (Tayassu pecari) have been recently shown to be susceptible to PCV2 and to display high infection prevalence (de Castro et al., 2014). These species…[Read more]

  • In general, the mentally unhealthy migrant workers in the current study experienced more symptoms related to O–C, I–S, and HOS. These findings were consistent with the results of Wong et al and Dai. O–C are characterized by irresistible thoughts, impulses, and actions that are unnecessary to the individual. I–S focuses on feelings of personal…[Read more]

  • Here, we adjusted a protocol and its corresponding acceptance parameters to measure FMDV-specific anamnesic IFN-γ responses, using a large number (n=308) of whole blood samples from naive and FMD-vaccinated cattle. Homologous and heterologous responses were evaluated in groups of animals immunized with O1/Campos, A/Arg/01 or A24/Cruzeiro…[Read more]

  • Frederick Lloyd posted an update 2 weeks ago

    Dorsal wedging of the TTB was not significantly associated with increasing severity of OA for grades 0–2 in the DIT and TMT joints, which is in NF-κB Signaling Library to previous studies in foals, in which narrowing of the dorsal aspect of the third tarsal bone was associated with the development of OA (Fretz, 1980; Auer et al., 1982; Ruo…[Read more]

  • Considering the necessity of creating goals for obesity control during intervention programs, Masquio et al demonstrated that improvements in inflammatory state and Anti-diabetic Compound Library resistance were observed in adolescents (mean age 16.7 ± 1.6 years) who presented low-to-moderate weight loss (−7.64%) after 1 year of a multi…[Read more]

  • The SE-AFLP genotyping also enabled proper Corynebacterium species differentiation and further permitted the assessment of C. amycolatum heterogeneity. Although most of C. amycolatum strains originated from the same herd (H3), they presented greater variability regarding not only the SE-AFLP genotypes but also the antimicrobial susceptibility…[Read more]

  • ResultsDiscussionIn the first study, sarolaner at all doses, was highly effective for the treatment and control of flea and tick infestations on dogs for at least one month. Efficacy against fleas was 100% from treatment through Day 35 and>95% through Day 56. Ticks were less susceptible, though treatment at the lowest dose resulted in ∼100% c…[Read more]

  • The novel duck origin parvovirus (N-GPV) was determined to be causative agent of BADS in our previous study and found to be close related with goose parvovirus (Chen et al., 2015c). Similar to other members of the genus Anseriform dependoparvovirus 1 in the family Parvoviridae, the full-length genomic sequence of N-GPV is approximately 5kb and…[Read more]

  • Both VP1-98 and VP1-145 can modulate the positive charges at the five-fold axis that are required for heparin binding. The amino caspofungin residue at VP1-145 is reported as a molecular switch for PSGL-1 binding, as substitution of VP1–145G/Q to E completely diminished PSGL-1 binding (Nishimura et al., 2013). EV-A71 with VP1-E145 has the V…[Read more]

  • Frederick Lloyd posted an update 4 weeks ago

    Horses that had intestinal resection were at increased risk of incisional complications. Bacterial contamination of the abdominal incision site following incision into the intestinal lumen may increase the risk of surgical site infection (Honnas and Cohen, 1997). Another potential explanation is that resection is often required for strangulating…[Read more]

  • Considering that co-infection of the same cell with HIV-1 and other microbial pathogen is probably uncommon in vivo (Bertram et al., 1996), Tax still can stimulate HIV-1 reactivation from latent fasudil in a paracrine manner, where Tax can be secreted (Alefantis et al., 2005). Tax can act on HIV-1 expression directly at molecular levels, as shown…[Read more]

  • Frederick Lloyd posted an update 1 month ago

    Materials and methodsIn June and July 2010–2012, we collected blood samples (n=2225) from Canada geese from 116 locations (Fig. 1) in Pennsylvania during banding and nuisance removal programs. Blood samples were collected from the medial metatarsal vein from geese being released and by cardiocentesis from birds that were euthanized. Blood s…[Read more]

  • Frederick Lloyd posted an update 1 month ago

    Results13 TALEs (TALEs 1-13) were generated to target the HIV-1 promoter region in the proviral 5’LTR (nucleotide position −172 to −16), which also contains the tranylcypromine of natural transcription factors. The TALEs consisted of 17.5 repeats and recognized overlapping stretches of 19 nucleotides in the 5’LTR, respectively (Fig. 1). A non-HIV…[Read more]

  • It is interesting that in the before mentioned studies by Humby and O’Connor (2015), they could detect virion derived US28 that is brought into the Kasumi-3 topotecan during viral entry. In our studies, the US28 protein that is expressed in the monocytes is due to de novo production of US28 protein that is not apparent until 3–4 days post…[Read more]

  • Turkey is a country known for its unique geography that bridges continents and cultures. It also bridges several tectonic plates including the Eurasian, African, and Arabian plates through the Anatolian plate (Bommer et al., 2002). Interactions between all surrounding plates and the Anatolian plate produce an active seismic region that encompasses…[Read more]

  • IntroductionDental pulp is a loose connective tissue, which is located within a rigid, mineralized compartment enclosed by enamel and dentin. Throughout one’s life, pulp tissue may be attacked by external stimuli such as bacteria, trauma, and restorative materials. Pulp tissue has an intrinsic capacity to repair and regenerate when suffering from…[Read more]

  • Materials and methodsResultsTable 1 shows comparison between normal and obese individuals as regards systolic blood pressure, diastolic blood pressure, HOMA IR, HOMA B Index, T-cholesterol, triglycerides, HDL-C and LDL-C in children and adults. There is a significant increase in blasticidin secretion among obese children represented by HOMA B…[Read more]

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