Dock Miles

  • As health information technology advances, more and more innovations are being developed to engage people with their health data for various health-enhancing applications. Notable innovations include adopted in the US,, or in Australia, and under the United Kingdom’s National Health Service.Such a system is also under development in Taiwan,…[Read more]

  • Other MRSA from horses attributed to clonal complex CC8The occurrence of MRSA ST247, t051, IV in horses (Cuny et al., 2016) was at first glance surprising as MRSA ST247,t051 are known as an epidemic HA-MRSA which was widely disseminated in a number of European countries in the 1990ties (Witte et al., 2008). As this HA-MRSA contains SCCmecI, a…[Read more]

  • Compared to E. coli, no studies have determined the relationship between TolC and IWR-1-endo tolerance in Salmonella, infection with which is a potential public threat. Our study showed that the TolC membrane protein is required for S. Choleraesuis survival, expression of adequate acid-mediated genes, and maintenance of its normal morphology in…[Read more]

  • Baseline characteristics of cows were similar, except for the number of DIM at diagnosis, which differed between treatment groups despite randomisation (P = 0.04, Welch two sample t test). Therefore, all models were corrected for DIM to distinguish between the effects of treatment and stage of lactation. For plasma BHBA, glucose and insulin con…[Read more]

  • TGBp2, which possesses two transmembrane domains, is an integral membrane protein of endoplasmic reticulum (ER) and ER-derived granular vesicles (Solovyev et al., 2000; Mitra et al., 2003; Ju et al., 2005, 2007; Samuels et al., 2007; Hsu et al., 2008), with its short N- and C-terminal tails exposed to the cytosol (Hsu et al., 2008) and its central…[Read more]

  • The different studies mentioned above all have used various programs to identify and validate the best two or three reference genes. These are: geNorm, NormFinder and BestKeeper, for viruses in tomato (Mascia et al., 2010) and Nicotiana benthamiana (Liu et al., 2012); geNorm, NormFinder and two-way ANOVA, for barley yellow dwarf virus in cereals…[Read more]

  • In this study, we have found that five out of ten human GBS strains could infect tilapia with mortality of 56.67–100%. Among them, two strains were serotype III, one strain was serotype Ia and another one was serotype V. Among the five human GBS strains unable to infect tilapia, one was serotype III, three were serotype Ia and the other was s…[Read more]

  • Using high-throughput sequencing of immunoprecipitated RNA after cross-linking (CLIP-Seq), many lncRNA-protein interactions have been identified and included in the Starbase database (Li et al., 2014a). Based on information in this database, the differentially expressed lncRNAs identified here should have the potential to interact with 33 RBPs of…[Read more]

  • Dock Miles posted an update 2 weeks ago

    AcknowledgmentThe authors wish to extend their appreciation to the Deanship of Scientific Research at King Saud University for funding the work through the research group Project No. RGP-VPP-238.IntroductionInsulin-like growth factor binding proteins (IGFBPs) belong to a family of at least six homologous proteins that bind insulin-like growth…[Read more]

  • Following PO administration of FLU, horses showed mean terminal plasma elimination half-lives in between those reported in cats (13.6 h) and dogs (7.1 h) (De Vito et al., 2014a and b). This is consistent with the clearance value of FLU in horses which is smaller than that reported in dogs (604 mL/h/kg) and larger than that reported in cats (195 m…[Read more]

  • An alternative hypothesis is that poor, or near lack of, binding of trimers or glycosylated envelope proteins to α4β7 integrin might mean that α4β7 integrin plays no significant role in HIV-1 infection, as was reported in studies where infectious molecular clones (IMCs) and pseudoviruses were used for infection in in vitro (Parrish et al., 201…[Read more]

  • Yet, it scopolamine hydrobromide was at the international level that Russian support proved most effective. Trying to avoid isolation, Moscow mobilized a group of influent allies in favour of its Syrian ally. The BRICS (Brazil, Russia, India, China, and South Africa) are major emerging economic powers that share the explicit goal of replacing…[Read more]

  • Given the kinetics of antibody responses (Tizard, 2013b), it is perhaps more likely that the mechanism of early protection is innate immune responses, effectuated by type I dpn and other pro-inflammatory cytokines, that are stimulated by ‘danger signals’ (bacterial and viral biochemical motifs) (Matzinger, 1994; Kumar et al., 2011) in IN vacc…[Read more]

  • The PI3K/Akt signaling pathway modulates metabolism and promotes cell survival, growth and cap-dependent translation (reviewed in Manning and Cantley (2007)). Under physiological conditions stimulation of cell surface receptors, such as the platelet-derived growth factor receptor (PDGFR), leads to activation of the PI3K/Akt signaling cascade.…[Read more]

  • We observed that there was a predominance of lymphocytes expressing TCRαβ in the CSF, which also occurs in healthy dogs (Tipold et al., 1998). This phenotype was reported predominantly in the tissues of healthy dogs, as intestinal lamina propria (German et al., 1999), respiratory tract and in the alveolar interstitium of dogs, while TCRγδ cel…[Read more]

  • IntroductionThe Bartholin’s gland is situated deep in the posterior part of the labium majus, measuring 8–10mm in diameter and has no capsule. Its function is to produce mucus as a lubricant upon sexual arousal. The secreted mucus empties into the Bartholin’s duct which measures approximately 2.5cm in length and opens in the vulvar vestibulum h…[Read more]

  • IntroductionMethicillin-susceptible (MSSA) and methicillin-resistant S. aureus (MRSA) occur as commensal colonizers of skin and mucosa in healthy humans and animals (Graveland et al., 2011). However, they can cause severe infections and treatment might be hampered due to the development of resistances against different antimicrobial agents.The…[Read more]

  • Dock Miles posted an update 4 weeks ago

    While the tadpole type III (and type I) IFN receptor gene expression is significantly reduced within a short time of FV3 infection, the adult frog type I IFN receptor expression is significantly upregulated. This may, at least in part, explain the relative tadpole sensitivity to FV3 as compared to the relatively resistant adult frogs and likely…[Read more]

  • Dock Miles posted an update 4 weeks ago

    MethodsResultsDiscussionConclusionConflicts of interestAcknowledgmentsIntroductionThe game of soccer is associated with frequent intermittent high-intensity exercise, and success in soccer depends on various factors related to match play, including tactical, technical, mental, and physiological characteristics of players. Key elements of the game…[Read more]

  • Dock Miles posted an update 1 month ago

    The study included CSF samples from 10 dogs with MUO, along with serum samples from nine of these dogs (see : ). Guidelines for diagnosis of MUO were based on clinical findings, advanced diagnostic imaging and CSF analysis; additional histopathology confirmed granulomatous meningoencephalomyelitis in three dogs and necrotising leucoencephalitis in…[Read more]

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